If architecture and stone sculpture captures your fancy, Viseu is definitely worth visiting. In addition, the red wine from the Dao region is considered to be Portugal’s finest. 

If you fancy a picturesque village, Piódão is the perfect place. Its terraced slopes and stone villages offer highly rewarding views. 

Also known as the Venice of Portugal, Aveiro has an energetic vibe. Its a lovely place best explored on foot or moliceiro (the traditional seaweed-harvesting boat now converted to tourist use)

Fabulous for hiking, there are several trails in the region, from easy to difficult levels. Penhas Douradas, 700 m above Manteigas has a stunning view. You can also drive up here and stay at one of the hotels. 

Most famous for its university which is the oldest in Portugal, Coimbra is a picturesque city along the banks of River Mondego.